Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 44 4 2015 04 15 551 60 Hamed Alaghemandan Dept. of Health Management in Disaster and Emergency, Engineering Research Institution of Natural Disaster Management, Shakhes Pajouh, Isfahan, Iran. Mohsen Ghaffari Darab Dept. of Business Management, Mobarakeh Branch, Islamic Azad University, Mobarakeh, Isfahan, Iran AND Dept. of Health Services Management, Isfahan University of Medical Sciences, Isfahan, Iran. Elahe Khorasani Dept. of Health Services Management, Isfahan University of Medical Sciences, Isfahan, Iran AND Dept. of Pharmacoeconomics and Pharmaceutical Administration, School of Pharmacy, Students' Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran. Ehsan Namazi Shefa Drug Rehabilitation Center, Isfahan, Iran. Mohammad Hossein Maniyan Shefa Drug Rehabilitation Center, Isfahan, Iran. Maryam Barati Dept. of Health Services Management, Isfahan University of Medical Sciences, Isfahan, Iran. 2015 10 14 Background: : Addiction is one of the most serious social damages and due to its progressive nature in all aspects,  adversely affects people’s physical and psychological health. Hence, this paper investigates the characteristics of drug addicts in a drug rehabilitation center in the city of Isfahan. Methods: In this cross-sectional study conducted in 2012, the population consisted of all addicts that referred to Shefa Drug Rehabilitation Center. A sample of 201 individuals was selected randomly. Two questionnaires were drawn up to collect data; the first questionnaire examined demographic characteristics and the second was the 71-item Minnesota Multiphase Personality Inventory short form. Chi-square test, Fisher’s exact test and Kruskal-Wallis test were used in SPSS20 to analyze the data. Results: Overall, 98% of participants were men, 65.7% were married, and 13.3% were unemployed. Depression and  hypomania were respectively the most and the least prevalent disorders among individuals with high-risk psychological profiles of clinical scales respectively. Psychopathic deviation and schizophrenia were seen among the unemployed more than the employed ones. Conclusion: Considering the fact that depression was the most common personality disorder among the addicts participating, it is recommended that this disorder be given priority in investigations in the treatment programs of these patients.  In addition, the scales of disorder, schizophrenia, mental infirmity, mental deviation, and paranoia had a significant relationship to aggression, delirium and hallucination, which must be taken into consideration in the treatment of such patients. https://ijph.tums.ac.ir/index.php/ijph/article/view/3585 https://ijph.tums.ac.ir/index.php/ijph/article/download/3585/3260