Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 53 6 2024 06 11 1236 1245 Kuantkan Zhabagin Administrative Department, Semey Nuclear Medicine and Oncology Center, Semey, Kazakhstan Almagul Zhabagina Department of Clinical Oncology and Nuclear Medicine, Semey Medical University, Semey, Kazakhstan Gulnar Shalgumbayeva Department of Family Medicine, Semey Medical University, Semey, Kazakhstan Dina Toleutayeva Department of Epidemiology and Biostatistics, Semey Medical University, Semey, Kazakhstan Ainur Baissalbayeva Research Department, “UMIT” International Oncological Center of TomoTherapy, Astana, Kazakhstan Tolegen Toleutayev Department of Cardiovascular and Thoracic Surgery Named by B.S.Bulanov, Semey Medical University, Semey, Kazakhstan Zhansaya Telmanova 1. Department of Public Health, Central Asian Institute for Medical Research, Astana, Kazakhstan 2. Department of Science, Asian Pacific Organization for Cancer Prevention, Bishkek, Kyrgyzstan Nurbek Igissin 1. Department of Public Health, Central Asian Institute for Medical Research, Astana, Kazakhstan 2. Department of Science, Asian Pacific Organization for Cancer Prevention, Bishkek, Kyrgyzstan 3. Research Institute of Life and Health Sciences, Higher School of Medicine, Kokshetau University Named after Sh.Ualikhanov, Kokshetau, Kazakhstan Malcolm Moore Department of Science, Asian Pacific Organization for Cancer Prevention, Bishkek, Kyrgyzstan 2023 08 02 2023 12 10 Colorectal cancer (CRC) is a major contributor to global cancer cases and deaths, making it a significant public health concern. As the number of CRC survivors continues to rise, understanding the impact of CRC and its treatment on their quality of life (QoL) has become increasingly important. The determinants of QoL in CRC patients are multifaceted and include physical health, physical fitness, physical activity, healthy eating, psychological health, social support, the availability of high-quality medical care, and QoL at the end of life. These factors interact to shape the overall well-being of CRC survivors. To enhance the QoL of CRC patients, a comprehensive approach is needed. This includes tailoring treatments to individual patient characteristics, providing psychological support and symptom management, promoting post-treatment rehabilitation, organizing support groups, emphasizing early detection, and effectively managing CRC-related symptoms. Addressing these aspects can significantly improve the QOL and well-being of CRC survivors, helping them adapt to life after treatment and thrive in the face of the challenges they may encounter.   https://ijph.tums.ac.ir/index.php/ijph/article/view/32768 https://ijph.tums.ac.ir/index.php/ijph/article/download/32768/8256