Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 38 2 2009 06 15 130 133 MA Boroumand Tehran Heart Center, Tehran University of Medical Sciences, Iran H Akhyani Tehran Heart Center, Tehran University of Medical Sciences, Iran M Sheikhvatan Tehran Heart Center, Tehran University of Medical Sciences, Iran S Hekmat Yazdi Reference Laboratories of Iran Research Center, Iran R Saboorian Reference Laboratories of Iran Research Center, Iran Sh Hashemi Tehran Heart Center, Tehran University of Medical Sciences, Iran F Firouzkouhi Tehran Heart Center, Tehran University of Medical Sciences, Iran 2015 10 03 Background: Resistance patterns among nosocomial bacterial pathogens in hospitals may vary widely from country to coun­try at any given point and within the same country over time. Acinetobacter baumannii is one of the most important bacte­rium causes hospital acquired infections. Therefore, surveillance of antibiotic resistance of A. baumannii is necessary, espe­cially in our country which there is no have much data in this field. Methods: In a prospective study, strain comprised of a total of 191 recent clinical isolates selected consecutively from clini­cal infections of separate patients from three University hospitals in Tehran. Minimum inhibitory concentration (MIC) of these organisms for imipenem, ciprofloxacin and ceftazidime was determined using E test method according to CLSI guide­line. Also, MIC50 and MIC90 percent was calculated for each of these antibiotics. Results: The percentages of Acinetobacter baumannii isolates susceptible to ciprofloxacin and ceftazidime by E test were 55.5% and 44.5%, respectively. The percentage of bacterium susceptible to imipenem by E test was 72.8%. MIC50 and MIC90 of imipenem in E test were 1.5 and >32, respectively. Conclusion: High antimicrobial resistance against A. baumannii species has been seen in Iran; therefore, it is necessary to imple­ment some approaches for prevention of bacterial spread. https://ijph.tums.ac.ir/index.php/ijph/article/view/3199 https://ijph.tums.ac.ir/index.php/ijph/article/download/3199/2998