Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 50 2 2021 02 01 232 244 Mehrdad ASKARIAN 1. Department of Community Medicine, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran 2. Health Behavior Science Research Center, Shiraz University of Medical Sciences, Shiraz, Iran Gary GROOT Department of Community Health and Epidemiology, College of Medicine, University of Saskatchewan, Saskatoon, Canada Ehsan TAHERIFARD Department of Internal Medicine, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran Erfan TAHERIFARD Department of Internal Medicine, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran Hossein AKBARIALIABAD Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran Roham BORAZJANI Trauma Research Center, Shahid Rajaee (Emtiaz) Trauma Hospital, Shiraz University of Medical Sciences, Shiraz, Iran Ardalan ASKARIAN College of Arts & Science, University of Saskatchewan, Saskatoon, Canada Mohammad Hossein TAGHRIR Department of Community Medicine, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran 2020 12 10 2021 01 11 Abstract Background: The necessity of easing pandemic restrictions is explicit. Due to the harsh consequences of lockdowns, governments are willing to find reasonable pathways to reopen their activities. Methods: To find out the basics of developing a reopening roadmap, on 6th-10th July 2020, we conducted a systematic search on PubMed, Scopus, and Web of Science to review the databases; and Google by manual to review the grey literature. Two independent authors extracted the data, and the senior author solved the discrepancies. Results: Sixteen documents were included. Data categorized into four sections: principals, general recommendations for individuals, health key metrics, and in-phases strategy. The number of phases or stages differed from three to six, with a minimum of two weeks considered for each one. Health key metrics were categorized into four subsets: sufficient preventive capacities, appropriate diagnostic capacity, appropriate epidemiological monitoring, and sufficient health system capacity. These metrics were used as the criteria for progressing or returning over the roadmap, which guarantees a roadmap's dynamicity. Noticeably, few roadmaps did not mention the criteria that may alter the dynamicity of their roadmap. When some areas face new surges, the roadmap's dynamicity is essential, and it is vital to describe the criteria to stop the reopening process and implement the restrictions again. Conclusion: Providing evidence for policymaking about lifting the COVID-19 restrictions seems to be missed in the literature should be addressed more, and further studies are recommended. https://ijph.tums.ac.ir/index.php/ijph/article/view/23133 https://ijph.tums.ac.ir/index.php/ijph/article/download/23133/7123