Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 50 8 2021 07 22 1555 1563 Mousa Ghelichi-Ghojogh Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran Haleh Ghaem Non-Communicable Diseases Research Center, Department of Epidemiology, School of Health, Shiraz University of Medical Sci-ences, Shiraz, Iran Fateme Mohammadizadeh Non-Communicable Diseases Research Center, Department of Epidemiology, School of Health, Shiraz University of Medical Sciences, Shiraz, Iran Mouhebat Vali Urology Research Center, Al-Thora Hospital, Department of Urology, Ibb University of Medical Sciences, Ibb, Yemen Faisal Ahmed Urology Research Center, Al-Thora Hospital, Department of Urology, Ibb University of Medical Sciences, Ibb, Yemen Soheil Hassanipour Gastrointestinal and Liver Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran Hossein-Ali Nikbakht Social Determinants of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran Fateme rezaei Department of Social Medicine, Jahrom University of Medical Sciences, Jahrom, Iran Mohammad Fararouei HIV/AIDS Research Center, School of Health, Shiraz University of Medical Sciences, Shiraz, Iran 2020 11 21 2021 03 06 Background: End-Stage Renal Disease (ESRD) is an irreversible impairment of kidney function that leads to permanently dependent on alternative therapies such as hemodialysis, peritoneal dialysis, and renal transplantation. This study aimed to systematically investigate the survival rate of patients with renal transplantation, graft, and its related factors in Iran. Methods: This systematic review and meta-analysis drew on articles indexed in six international and one internal databases (Medline/PubMed, ProQuest, Scopus, Embase, SID, and Web of knowledge) until Nov 2020. The reporting of the present study was performed in terms of PRISMA statement. All analyzes were performed using the STATA software. Results: Overall, 367 titles from 6 databases were evaluated of which 86 articles met the inclusion criteria. According to the random model, the graft survival rate at one, three, five, and 10 years were 92.48%, 85.08%, 79.96% and 68.15% respectively. Additionally, the patient survival rates at one, three, five, and 10 years were 91.27%, 86.46%, 81.17% and 78.15% respectively. There was a significant relationship between the age recipient and three-year graft survival rate (P=0.021). Additionally, there was an inverse and significant relationship between the donor age and 10-year patient survival rate (P=0.011). Conclusion: The patient and graft survival in transplanted kidney patients is comparable with most developed countries. https://ijph.tums.ac.ir/index.php/ijph/article/view/22951 https://ijph.tums.ac.ir/index.php/ijph/article/download/22951/7313