Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 36 4 2007 12 15 20 25 M Talebi SS Eshraghi MR Pourshafie MR Pourmand MR Eshraghian 2015 10 03 Background: To determine the species distribution, updated drug susceptibility patterns and genes conferring resistance in clini­cal vancomycin resistant enterococcal (VRE) isolates. Methods: Clinical enterococcal isolates collected during 7 months, from September 2005 to April 2006 from hos­pitalized pa­tients and outpatients were studied. Twenty five VRE were isolated from 450 enterococci samples (5.6%). VRE isolates were subjected to antibiotic susceptibility tests. Genotype of these isolates was determined by PCR. Results: All of the isolates were E. faecium and carried the vanA gene.  Antibiotic susceptibility tests showed that the iso­lates were resistant to ampicillin 25(100%), ciprofloxacin 25(100%), gentamicin 24(96%), erythromycin 25(100%), tetracy­clin 10(40%) and chloramphenicol 2(8%). Conclusion: VRE strains were resistant to three antibiotics and were susceptible to new antibiotics linezolid and dalfopris­tin-quinupristin. Switching to treatment with these antibiotics would relieve the problem for a short time. https://ijph.tums.ac.ir/index.php/ijph/article/view/2086 https://ijph.tums.ac.ir/index.php/ijph/article/download/2086/2067