<?xml version="1.0"?>
<Articles JournalTitle="Iranian Journal of Public Health">
  <Article>
    <Journal>
      <PublisherName>Tehran University of Medical Sciences</PublisherName>
      <JournalTitle>Iranian Journal of Public Health</JournalTitle>
      <Issn>2251-6085</Issn>
      <Volume>49</Volume>
      <Issue>Supple 1</Issue>
      <PubDate PubStatus="epublish">
        <Year>2020</Year>
        <Month>04</Month>
        <Day>28</Day>
      </PubDate>
    </Journal>
    <title locale="en_US">"Five-Early" Model: The Magic Weapon against COVID-19</title>
    <FirstPage>82</FirstPage>
    <LastPage>86</LastPage>
    <AuthorList>
      <Author>
        <FirstName>Qingjie</FirstName>
        <LastName>YI</LastName>
        <affiliation locale="en_US">Chongqing University Three Gorges Hospital, Chongqing 404100, China AND	Quality Control Department of Chongqing Three Gorges Central Hospital, Chongqing 404100, China</affiliation>
      </Author>
      <Author>
        <FirstName>Wei</FirstName>
        <LastName>FANG</LastName>
        <affiliation locale="en_US">Chongqing University Three Gorges Hospital, Chongqing 404100, China AND	Pharmaceutical Department of Chongqing Three Gorges Central Hospital, Chongqing 404100, China</affiliation>
      </Author>
      <Author>
        <FirstName>Chunhui</FirstName>
        <LastName>LANG</LastName>
        <affiliation locale="en_US">Chongqing University Three Gorges Hospital, Chongqing 404100, China AND	Department of Clinical Nutrition, Chongqing Three Gorges Central Hospital, Chongqing 404100, China</affiliation>
      </Author>
      <Author>
        <FirstName>Huaming</FirstName>
        <LastName>MOU</LastName>
        <affiliation locale="en_US">Chongqing University Three Gorges Hospital, Chongqing 404100, China AND	Department of Cardiology, Chongqing Three Gorges Center Hospital, Chongqing 404100, China</affiliation>
      </Author>
      <Author>
        <FirstName>Jinglong</FirstName>
        <LastName>LV</LastName>
        <affiliation locale="en_US">Chongqing University Three Gorges Hospital, Chongqing 404100, China AND Department of Hematology, Chongqing Three Gorges Central Hospital, Chongqing 404100, China</affiliation>
      </Author>
      <Author>
        <FirstName>Suxin</FirstName>
        <LastName>WAN</LastName>
        <affiliation locale="en_US">Chongqing University Three Gorges Hospital, Chongqing 404100, China AND	Pharmaceutical Department of Chongqing Three Gorges Central Hospital, Chongqing 404100, China</affiliation>
      </Author>
      <Author>
        <FirstName>Lian</FirstName>
        <LastName>GUO</LastName>
        <affiliation locale="en_US">Chongqing University Three Gorges Hospital, Chongqing 404100, China AND	Department of Endocrinology, Chongqing Three Gorges Central Hospital, Chongqing  404100, China</affiliation>
      </Author>
      <Author>
        <FirstName>Yilin</FirstName>
        <LastName>WANG</LastName>
        <affiliation locale="en_US">Chongqing University Three Gorges Hospital, Chongqing 404100, China AND	Quality Control Department of Chongqing Three Gorges Central Hospital, Chongqing 404100, China</affiliation>
      </Author>
      <Author>
        <FirstName>Huawen</FirstName>
        <LastName>LIU</LastName>
        <affiliation locale="en_US">Chongqing University Three Gorges Hospital, Chongqing 404100, China AND	Department of Oncology, Chongqing Three Gorges Central Hospital, Chongqing 404100, China</affiliation>
      </Author>
      <Author>
        <FirstName>Qing</FirstName>
        <LastName>XIAO</LastName>
        <affiliation locale="en_US">Department of Hematology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China</affiliation>
      </Author>
      <Author>
        <FirstName>Chunqiu</FirstName>
        <LastName>LIU</LastName>
        <affiliation locale="en_US">Chongqing University Three Gorges Hospital, Chongqing 404100, China AND	Department of Nephrology, Chongqing Three Gorges Central Hospital, Chongqing 404100, China</affiliation>
      </Author>
      <Author>
        <FirstName>Min</FirstName>
        <LastName>HUANG</LastName>
        <affiliation locale="en_US">Chongqing University Three Gorges Hospital, Chongqing 404100, China AND	Department of General Medicine, Chongqing Three Gorges Central Hospital, Chongqing 404100, China</affiliation>
      </Author>
      <Author>
        <FirstName>Bangshuo</FirstName>
        <LastName>ZHANG</LastName>
        <affiliation locale="en_US">Chongqing University Three Gorges Hospital, Chongqing 404100, China AND	Department of Hematology, Chongqing Three Gorges Central Hospital, Chongqing 404100, China</affiliation>
      </Author>
    </AuthorList>
    <History>
      <PubDate PubStatus="received">
        <Year>2020</Year>
        <Month>04</Month>
        <Day>28</Day>
      </PubDate>
    </History>
    <abstract locale="en_US">Background: COVID-19(2019 novel coronavirus disease)has brought tremendous pressure to the prevention and control of the national epidemic due to its concealed onset, strong infectivity and fast transmission speed.
&#xD;

Methods: In this retrospective study, 226 patients diagnosed with 2019 novel coronavirus pneumonia (NCP) in the Chongqing University Three Gorges Hospital were included. The patients' clinical data, including general information, initial symptoms at the onset, time of disease diagnosis, time to treatment in hospital, time of nucleic acid conversion to negative, disease classification, total time of hospitalization were collected. The clinical data of the mild and severe patients were compared.
&#xD;

Results: Fever, cough, sore throat, poor appetite andfatigue were the main symptoms of the diagnosed patients. The time of diagnosis was significantly shorter in the mild patients (4.96 &#xB1; 4.10 days) than severe patients (7.63 &#xB1; 9.17 days) (P=0.004). Mild patients had shorter time to treatment in hospital (6.09 &#xB1; 4.47 vs. 8.71 &#xB1; 9.04 days) and less time of nucleic acid conversion to negative (7.58 &#xB1; 2.51 vs. 11.6 &#xB1; 4.67 days) compared to the severe patients.
&#xD;

Conclusion: The above results can be used as a quantitative basis for the &#x201C;five-early"(early detection, early screening, early diagnosis, early isolation treatment, and early recovery) model. The government, the masses, and the hospitals' joint prevention and optimization of the "five-early" model will provide important scientific reference for further prevention and control of the epidemics.
&#xD;

&#xA0;</abstract>
    <web_url>https://ijph.tums.ac.ir/index.php/ijph/article/view/20545</web_url>
    <pdf_url>https://ijph.tums.ac.ir/index.php/ijph/article/download/20545/6763</pdf_url>
  </Article>
</Articles>
