Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 34 1 2005 03 15 23 26 Z Jadali MB Eslami MH Sanati P Mansouri M Mahmoudi N Maghsoudi F Esfahanian 2015 10 03 Vitiligo is a common skin disorder, characterized by depigmented patches due to selective destruction of melanocytes. The etiology of this disease is unknown. A number of hypotheses including viral theory have been proposed to explain the etiology. To determine the prevalence of antibody to hepatitis C virus infection in vitiligo patients, the present study was performed. Third generation ELISA test was used for detection of antibodies to HCV in human sera. All normal controls were anti-HCV negative whereas only one patient was positive for anti-HCV and there was no significant difference in the prevalence of anti-HCV between patients and controls. These results indicate that hepatitis C virus has not a direct causal role in the pathogenesis of vitiligo, however, this does not rul out a "hit and run" virus induced disease. https://ijph.tums.ac.ir/index.php/ijph/article/view/1875 https://ijph.tums.ac.ir/index.php/ijph/article/download/1875/1856