Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 48 9 2019 09 03 1732 1734 Yu HE Department of Clinical Laboratory, The First Affiliated Hospital of Guangxi Medical University, Nanning, P.R. China Bo LIU Department of Clinical Laboratory, The First Affiliated Hospital of Guangxi Medical University, Nanning, P.R. China Hui-Ling WU Department of Clinical Laboratory, The First Affiliated Hospital of Guangxi Medical University, Nanning, P.R. China Shan HUANG Department of Clinical Laboratory, The First Affiliated Hospital of Guangxi Medical University, Nanning, P.R. China Yun-Wei QI Department of Clinical Laboratory, The First Affiliated Hospital of Guangxi Medical University, Nanning, P.R. China Hui-Han ZHAO Department of Nursing, The First Affiliated Hospital of Guangxi Medical University, Nanning, P.R. China Xue QIN Department of Clinical Laboratory, The First Affiliated Hospital of Guangxi Medical University, Nanning, P.R. China Shan LI Department of Clinical Laboratory, The First Affiliated Hospital of Guangxi Medical University, Nanning, P.R. China 2019 09 03 Chromosome aberration is associated with infertility and isochromosome is a rare chromosomal abnormality potentially associated with infertility or multiple miscarriages. Here we report a man of 29-yr-old diagnosed of infertility from China with rare isochromosome. Peripheral blood lymphocytes were obtained for chromosome G banding karyotyping. Hormones and other tests were performed. The semen analysis revealed Azoospermia. Complementary isochromosome of 46, XY, i(5)(p10),i(5)(q10) was identified. This is the first report of Complementary isochromosome of 46, XY, i(5)(p10),i(5)(q10).     https://ijph.tums.ac.ir/index.php/ijph/article/view/18263 https://ijph.tums.ac.ir/index.php/ijph/article/download/18263/6513