Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 48 9 2019 09 03 Frailty and Associated Risk Factors in Elderly People with Health Examination in Rural Areas of China 1663 1670 Jie GU Zhongshan Hospital of Fudan University, Shanghai 200032, P.R. China Haiying CHEN Xidu Community Health Center of the Fengxian District, Shanghai 201400, P.R. China Xiaoqing GU Xidu Community Health Center of the Fengxian District, Shanghai 201400, P.R. China Xiaomin SUN Health Development Institute of Pudong, Shanghai 201208, P.R. China Zhigang PAN Zhongshan Hospital of Fudan University, Shanghai 200032, P.R. China Shanzhu ZHU Zhongshan Hospital of Fudan University, Shanghai 200032, P.R. China Doris YOUNG Department of General Practice, Melbourne Medical School, The University of Melbourne, Melbourne, Australia 2019 09 03 Background: Frailty is a common syndrome in elderly people, but has not been fully studied in China. We aimed to investigate the epidemiological characteristics of frailty and analyze its risk factors in elderly people in rural areas of China. Methods: This cross-sectional study was conducted between September and October 2016. Overall, 4323 elderly people over 60 yr were enrolled by cluster random sampling method from the Fengxian District of Shanghai, China. These subjects voluntarily participated in the health examination of the 2016 National Basic Public Health Service Program. In addition to regular examination items, frailty assessment was performed on the basis of Fried frailty phenotype criteria. Results: The prevalence of pre-frailty and frailty was 49.4% and 6.8%, respectively. Advanced age (OR=1.44 for pre-frailty and OR=2.01 for frailty, 65-74 years old; OR=3.02 for pre-frailty and OR=14.13 for frailty,75-84 years old; OR=8.17 for pre-frailty and OR=71.71 for frailty, ≥85 years old), female (OR=1.32 for pre-frailty and OR=1.97 for frailty), stroke history (OR=1.75 for pre-frailty and OR=2.43 for frailty), vision decrease (OR=1.98 for pre-frailty and OR=2.70 for frailty), and anemia (OR=1.95 for pre-frailty and OR=3.64 for frailty) were common risk factors for both pre-frailty and frailty. Conclusion: Healthy elderly people in the rural areas of Shanghai have relatively high prevalence of pre-frailty and frailty. Advanced age, female, stroke history, decreased vision, and anemia are the risk factors for pre-frailty and frailty.   https://ijph.tums.ac.ir/index.php/ijph/article/view/18253 https://ijph.tums.ac.ir/index.php/ijph/article/download/18253/6505