Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 48 6 2019 06 02 Target Elimination-Denatured and Unstable Proteins, Environmental Toxins, Metabolic Wastes, Immunosuppressive Factors and Chronic Inflammatory Factors of Medical System for Chronic Diseases Prevention and Health Promotion: A Narrative Review 994 1003 Jiren ZHANG Guangdong Institute of Target Tumor Intervention and Prevention, Qingyuan, China Zhaojing JIANG Department of Radiation Oncology, Zhujiang Hospital, Sourthern Medical University, Guangzhou, China Wenjuan WEI Guangdong Institute of Target Tumor Intervention and Prevention, Qingyuan, China Xufeng LI Guangdong Institute of Target Tumor Intervention and Prevention, Qingyuan, China AND Institute of Economics, School of Social Sciences, Tsinghua University, Beijing, China Chen SUN Guangdong Institute of Target Tumor Intervention and Prevention, Qingyuan, China Yuanyuan ZHANG Guangdong Institute of Target Tumor Intervention and Prevention, Qingyuan, China Shilin FU Guangdong Institute of Target Tumor Intervention and Prevention, Qingyuan, China Jingfen ZHENG Guangdong Institute of Target Tumor Intervention and Prevention, Qingyuan, China 2019 06 02 Background: The incidence of chronic diseases, such as cardiovascular disease, diabetes, overweight, obesity, cancer and other diseases has been increasing. It is a huge challenge to public health industry about how to provide risk intervention and preventive medical services and explore advanced technology platform for effective prevention and control of chronic diseases. Methods: We collaborated domestic and international experts on preventive medicine, and analyzed pathogenesis and risk factors for the major chronic diseases. Results: We established Target Elimination--denatured and unstable proteins, environmental toxins, metabolic wastes, immunosuppressive factors and chronic inflammatory factor (TE-PEMIC) system that offer us the standard and methods to eliminate and intervene pathogenic factors of the chronic diseases. Conclusion: It provides new researches and exploring new ideas to prevent and intervene chronic diseases by applying the TE-PEMIC chronic diseases prevention medical technology system.   https://ijph.tums.ac.ir/index.php/ijph/article/view/17334 https://ijph.tums.ac.ir/index.php/ijph/article/download/17334/6403