Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 30 1-2 2001 06 15 37 40 M Ansari-Lari M Saadat M Shahryari DD Farhud 2015 10 03 Individuals handling antineoplastic drugs or their wastes may absorb these potent genotoxic agents. The effects of handling antineoplastic drugs were examined in a group of 24 nurses working in the hematology and oncology departments of two different university hospitals in Shiraz (Iran) and in a group of 18 unexposed nurses as control group. The cytogenetic repercussions of exposure were assessed by examining sister chromatid exchanges (SCEs) and micronuclei (Mn) in circulating lymphocytes. A significant increased frequencies of SCE and Mn is observed in circulating lymphocytes. A significant increased frequencies of SCE and Mn is observed in nurses in daily contact with antineoplastic drugs as compared to control group. https://ijph.tums.ac.ir/index.php/ijph/article/view/1671 https://ijph.tums.ac.ir/index.php/ijph/article/download/1671/1652