Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 48 Supple 1 2019 03 04 1 9 Ghobad MORADI Social Determinants of Health Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran Bakhtiar PIROOZI Social Determinants of Health Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran Cyrus ALINIA Department of Public Health, School of Health, Urmia University of Medical Sciences, Urmia, Iran Samaneh AKBARPOUR Center for Communicable Diseases, Ministry of Health and Medical Education, Tehran, Iran Mohammad Mehdi GOUYA Center for Communicable Diseases, Ministry of Health and Medical Education, Tehran, Iran Sima SAADI Department of Geography and Rural Planning, Faculty of Planning and Environmental Sciences, Tabriz University, Tabriz, Iran Amjad MOHAMADI BOLBANABAD Social Determinants of Health Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran Parvin AFSAR KAZAEROONI Center for Communicable Diseases, Ministry of Health and Medical Education, Tehran, Iran 2019 03 04 Background: This study aimed at estimating the incidence, mortality, burden, and geographical distribution of HIV/AIDS in Iran at national and provincial level during 2008-2016. Methods: We applied the Disability Adjusted Life Years (DALYs) index to assess the burden of HIV/AIDS on the basis of Years of Life Lost (YLLs) and Years Lived with Disability (YLDs). We used the Iranian life table of 2016 for treated and a fixed figure of 8 years as remaining length of life in untreated patients, 0.03 as discount rate, and 0.504 as disability weigh in both treated and untreated cases. The primary data was obtained from HIV/AIDS surveillance system. Results: The incidence of HIV/AIDS increased from 4440 cases in 2008 to 4928 cases in 2016. The mortality rate was 259 and 288 cases in 2008 and 2016, respectively, which was always higher among males than females. The burden of HIV/AIDS increased from 26231 DALYs in 2008 to 29114 DALYs in 2016. In addition, the population-adjusted burden of HIV/AIDS was not equally distributed among different provinces of Iran, and it was more concentrated in western regions of the country during the studied period. Conclusion: Although the trend of the national burden of HIV/AIDS did not change significantly over the past decade, it was alarming especially among males and among people living in some provinces such as Kermanshah, Lorestan, Hormozgan, and Tehran.     https://ijph.tums.ac.ir/index.php/ijph/article/view/16413 https://ijph.tums.ac.ir/index.php/ijph/article/download/16413/6306