Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 18 1-4 1989 12 15 1 8 D.D. FARHUD 2015 10 03 C3 typing was performed, by agarose gel electrophorisis, in 147 German patients suffering from hyperlipoproteinemia. The control group consisted of 322 healthy Germans. High frequencies of non-typeable sera, varying between 16.66 and 35.71% in different HLP types, found in the present investigation are notable and are a clue for chemical denaturation of C3 protein in HLP patients. Statistical analysis showed significant results (P.0.001) in all five HLP types, as well as in the total, in comparison with the control group. https://ijph.tums.ac.ir/index.php/ijph/article/view/1634 https://ijph.tums.ac.ir/index.php/ijph/article/download/1634/1615