Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 48 1 2019 01 16 132 138 Siavaah CHALABIANI Department of Molecular Diagnostics, Noor Pathobiology Laboratory, Tehran, Iran Mina KHODADAD NAZARI Department of Molecular Diagnostics, Noor Pathobiology Laboratory, Tehran, Iran Nada RAZAVI DAVOODI Department of Molecular Diagnostics, Noor Pathobiology Laboratory, Tehran, Iran Mahdi SHABANI Department of Immunology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran Masoud MARDANI Tropical Infectious Diseases Research Center, Shahid Behshti University of Medical Sciences, Tehran, Iran Abdolfatah SARAFNEJAD Department of Molecular Diagnostics, Noor Pathobiology Laboratory, Tehran, Iran AND Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Ali AKBAR AMIRZARGAR Department of Molecular Diagnostics, Noor Pathobiology Laboratory, Tehran, Iran AND Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran AND Molecular Immunology Research Center, Tehran University of Medical Sciences, Tehran, Iran 2019 01 16 Background: Brucellosis as a zoonotic disease is widespread among human and animal that it continues to be a major public health problem. Due to the shortage of recent epidemiologic data regarding the brucellosis distribution in Iran, we convinced to evaluate the prevalence of brucellosis in provinces of Iran. Methods: In this descriptive study, data were collected from brucellosis suspected patients referred to Noor Pathobiology Laboratory, Tehran, Iran from 18 out of 31 provinces of Iran during 2013-2015. Results: Overall, 2635 out of 17103 attending cases (15.4%) were recognized as brucellosis patients. The most prevalent rate was found in patients aged 20-39 yr old (41%) which of them 67% were male. Patients with brucellosis were significantly diagnosed in spring season (Apr to late May). Among included provinces, Hamadan Province had the highest (25%) prevalence followed by Markazi and Mazandaran with 24.7% and 22.5%, respectively. Conclusion: Brucellosis is still considered as an important infectious disease with a high prevalence in many provinces of Iran. It is necessary to implement a national brucellosis control program by increasing medical education, public knowledge and various controlling plans for preventing, controlling and eradicating of brucellosis.   https://ijph.tums.ac.ir/index.php/ijph/article/view/15948 https://ijph.tums.ac.ir/index.php/ijph/article/download/15948/6263