Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 49 5 2020 05 01 989 994 EN Moslem TAHERI SOODEJANI Research Center of Prevention and Epidemiology of Non-Communicable Disease, Department of Biostatistics and Epidemiology, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Seyyed Mohammad TABATABAEI Medical Informatics Department, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran Hamid Reza SHORAKA Vector-Borne Diseases Research Center, North Khorasan University of Medical Sciences, Bojnurd, Iran Hosein FALLAHZADEH Research Center of Prevention and Epidemiology of Non-Communicable Disease, Department of Biostatistics and Epidemiology, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Azimeh GHADERI Shahr-e-Kord Health Services Center, Shahr-e-Kord, Iran 2018 07 14 2018 09 24 Background: Congenital hypothyroidism is one of the most common endocrine disrupters and metabolism, and is one of the most important preventable causes of physical and mental disabilities. Methods: This was a case-control study, in which 54468 infants were screened from 2006 to 2014 in Shahre-Kord, western Iran. To describe the data, central and dispersion indices such as mean and standard deviation was used. For modeling, logistic regression was used. All the tests were performed at the significant level of 5%. Results: Overall, 111 cases were diagnosed with hypothyroidism, which made the prevalence value equal to 2 cases per 1000 births. The prevalence in females and males was 1.9 and 2.2 per 1,000 birth, respectively. The odds ratio for this disorder was 4.47(2.42-9.28) for the neonates with a family history of hypothyroidism and 1.72(1.05-2.82) for those born through cesarean. Conclusion: The incidence of this disorder is similar in males and females, and the incidence of this disease in people with a family history is far more than others. https://ijph.tums.ac.ir/index.php/ijph/article/view/14023 https://ijph.tums.ac.ir/index.php/ijph/article/download/14023/6922