Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 46 8 2017 07 17 1123 1131 Ghodratollah ROSHANAEI Modeling of Noncommunicable Diseases Research Center, Dept. of Biostatistics and Epidemiology, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran Masoud SABOURI GHANNAD Research Center for Molecular Medicine, Dept. of Microbiology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran Jalal POOROLAJAL Research Center for Health Sciences, Dept. of Epidemiology & Biostatistics, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran Minoo MOHRAZ Iranian Research Center for HIV/AIDS, Iranian Institute for Reduction of High-Risk Behaviors, Tehran University of Medical Sciences, Tehran, Iran Leila MOLAEIPOOR Dept. of Epidemiology and Biostatistics, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran 2017 07 17 2017 07 17 Background: The number of deaths related with co-infection of tuberculosis (TB) and HIV remains inappropriately high worldwide. TB is anticipated to be the major reason of HIV-related deaths globally. This study aimed to find out and evaluate the characteristics of the possible risk factors influencing the survival time of co-infected patients with HIV/TB in Tehran the capital of Iran. Methods: This retrospective study was performed on the referred patients to the one of two Behavioral Diseases Coun­seling Centers, Imam Khomeini, and Zamzam Centers, Tehran, Iran, in 2004-2013. Data were analyzed by Cox PH model utilizing SPSS16 statistical software. Results: Multivariate analysis confirmed that the age at diagnosis (P=0.014), gender (P=0.002), sexual transmission (P=0.01), cotrimoxazole preventive therapy (P<0.001), and onset to TB after post-HIV diagnosis (P=0.01) were the parameters which had significant effects on the death of HIV/TBco-infected patients. Conclusion: The results, recommend interplay between different risk factors and the risk of death in co-infected patients with HIV/TB. We presented the barriers to higher-level organizational and functional integration for commitment to interfere with the modifiable risk factors, which effect on the mortality of patients.   https://ijph.tums.ac.ir/index.php/ijph/article/view/10614 https://ijph.tums.ac.ir/index.php/ijph/article/download/10614/5260