Association between Probiotic Yogurt Intake and Gestational Diabetes Mellitus: A Case-Control Study

  • XiaoQian CHEN School of Nursing, Fujian Medical University, Shangjie Zhen, Fuzhou, Fujian, China
  • XiuMin JIANG Fujian Maternal and Child Health Hospital, Fujian Medical University, Fuzhou, Fujian, China
  • XinXin HUANG Fujian Maternal and Child Health Hospital, Fujian Medical University, Fuzhou, Fujian, China
  • HongGu HE Alice Lee Centre for Nursing Studies, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
  • Jing ZHENG School of Nursing, Fujian Medical University, Shangjie Zhen, Fuzhou, Fujian, China
Keywords: Case-control study; Chinese; Gestational diabetes mellitus; Probiotic yogurt

Abstract

Abstract Background: Gestational diabetes mellitus is one of the most frequent metabolic complications of pregnancy. Previous studies have reported that using either probiotic yogurt or a probiotic supplement reduces the incidence of gestational diabetes. However, the results were inconsistent. Thus, the aim of the present study was to investigate the association between gestational diabetes mellitus and probiotic yogurt intake during pregnancy and pre-pregnancy in Chinese women. Methods: This was a case-control study involving 123 cases with gestational diabetes mellitus and 126 controls matched for age and pre-pregnancy body mass index. Each participant was interviewed face-to-face using a structured questionnaire to collect socio-demographic characteristics, diet and exercise habits, as well as probiotic yogurt consumption (containing Lactobacillus acidophilus and Bifidobacterium) during pregnancy and pre-pregnancy. An unconditional logistic regression analysis was used to analyze the data. Results: Mothers in both groups had similar socio-demographic backgrounds. Probiotic yogurt intake during pregnancy was significantly higher in normal pregnant women than that in women with gestational diabetes mellitus (adjusted odds ratio: 0.292, 95% confidence interval: 0.148 - 0.577, P < 0.05). There were no significant differences in probiotic yogurt consumption before pregnancy between cases and controls. Conclusion: Probiotic yogurt intake before pregnancy was not associated with gestational diabetes mellitus, but probiotic yogurt consumption during pregnancy was effective in reducing the risk of gestational diabetes mellitus in Chinese women. The findings from the present study may have implications for the future care of pregnant Chinese women with gestational diabetes mellitus.    

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Published
2019-07-01
How to Cite
1.
CHEN X, JIANG X, HUANG X, HE H, ZHENG J. Association between Probiotic Yogurt Intake and Gestational Diabetes Mellitus: A Case-Control Study. Iran J Public Health. 48(7):1248-1256.
Section
Original Article(s)