Prevalence of Vitamin D Deficiency during Second Trimester of Pregnancy in Shanghai China, Risk Factors and Effects on Pregnancy Outcomes

  • Ling YANG Dept. of Obstetrics, Changning Maternity and Infant Health Hospital, Shanghai, China
  • Lige SONG Dept. of Endocrinology, Tongji Hospital, School of Medicine, Tongji University, Shanghai, China
  • Xiao XU Dept. of Endocrinology, Tongji Hospital, School of Medicine, Tongji University, Shanghai, China
  • Yihan LIU Dept. of Endocrinology, Tongji Hospital, School of Medicine, Tongji University, Shanghai, China
  • Huijuan LI Dept. of Endocrinology, Tongji Hospital, School of Medicine, Tongji University, Shanghai, China
  • LongYing TANG Dept. of Obstetrics, Changning Maternity and Infant Health Hospital, Shanghai, China
Keywords: Vitamin D deficiency, Second trimester of pregnancy, Prevalence, Risk factor, Pregnant outcome

Abstract

AbstractBackground: Vitamin D plays important roles in various physiological processes. Vitamin D deficiency is common among pregnant women in some regions, such as China. Our study aimed to determine the prevalence of Vitamin D deficiency during second trimester of pregnancy in Shanghai China, and explore its risk factors and effects on pregnant outcomes.Methods: Overall, 23100 pregnant women (2013 to 2017, Shanghai, China) were included and vitamin D concentrations were measured at 16 weeks of gestation. Correlations between vitamin D concentrations and participants’ general data and maternal and infant outcomes were analyzed by chi square test. Non-conditional multivariate logistic regression analysis was used to screen the independent risk factors for vitamin D deficiency.Results: Vitamin D deficiency was significantly correlated with aging, education level, smoking, dirking, BMI before pregnancy, body weight gain during pregnancy (P<0.01), the use of vitamin D supplement and milk consumption, and older than 30 years, drinking, smoking, BMI before pregnancy> 36, body weight gain during pregnancy< 40g per day, no daily milk consumption, no vitamin D supplement, and education lever below college were independent risk factors for vitamin D deficiency in second trimester of pregnancy. In addition, vitamin D deficiency in second trimester of pregnancy was closely correlated with the occurrence of a serious of adverse maternal and infant outcomes.Conclusion: Vitamin D deficiency was still common among women in second trimester of pregnancy in Shanghai China. Vitamin D deficiency was closely correlated with the occurrence of a serious of adverse maternal and infant outcomes. 

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Published
2018-08-01
How to Cite
1.
YANG L, SONG L, XU X, LIU Y, LI H, TANG L. Prevalence of Vitamin D Deficiency during Second Trimester of Pregnancy in Shanghai China, Risk Factors and Effects on Pregnancy Outcomes. IJPH. 47(8):1145-50.
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Original Article(s)