Iranian Journal of Public Health 2018. 47(1):64-69.

Mild Hypothermia Therapy for Moderate or Severe Hypoxic-ischemic Encephalopathy in Neonates
Weihua LIAO, Huiying XU, Jing DING, Hong HUANG



Background: To study the nursing method of mild hypothermia therapy for moderate or severe hypoxic-ischemic encephalopathy (HIE) in neonates.

Methods: According to the inclusion and exclusion criteria, 48 patients were selected from Nanfang Hospital from December 2015 to October 2016 and randomly divided into the control group (n=24) and observation group (n=24). The control group received routine treatment and nursing, while the observation group received the same treatment as the control group combined with mild hypothermia treatment and nursing. The clinical effects were compared.

Results: The total effective rate in the observation group was increased and mortality was decreased, and the differences were statistically significant (P=0.029 and 0.033, respectively).  The 28 d neonatal behavioral neurological assessment and nursing satisfaction scores in the observation group were higher than those in the control group, and the differences were statistically significant (P=0.017 and 0.008, respectively).

Conclusion: Mild hypothermia therapy for moderate or severe HIE in neonates is safe and effective, and the correct nursing method is important for guaranteeing proper clinical treatment.




Hypoxic-ischemic encephalopathy, Neonates, Mild hypothermia, Nursing

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